Recombinant LIGHT, Human, AF

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Recombinant LIGHT, Human, AF
SDS- PAGE analysis of recombinant human LIGHT
Recombinant LIGHT, Human, AF
Recombinant LIGHT, Human, AF
Recombinant LIGHT, Human, AF
Recombinant LIGHT, Human, AF
Recombinant LIGHT, Human, AF
Recombinant LIGHT, Human, AF
Recombinant LIGHT, Human, AF
Recombinant LIGHT, Human, AF
Recombinant LIGHT, Human, AF
Recombinant LIGHT, Human, AF
Recombinant LIGHT, Human, AF

产品简介

产品简介

Catalog No.

PY2252

Source

Human Cytokines

UniProt ID

Reactivity

Measure by its ability to induce cytotoxicity in HT-29 cells in the presence of IFN-gamma. The ED50 for this effect is <23 ng/mL. Measure by its ability to induce proliferation in HUVEC cells. The ED50 for this effect is <3 ng/mL.

Application

Cell culture, Elisa

Calculated Mol Weight

20 kDa

Observed Mol Weight

17 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

TNFSF14, HVEM-L, CD258, LTg

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the C-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 0.1% sarkosyl in 1X PBS, pH 8.0.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

LIGHT is a member of the TNF family of ligands, and can conduct signaling through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or binding to a decoy receptor, DcR3. LIGHT generally expresses in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT can also activate NF-κB, to co-stimulate the activation of lymphocytes and induce apoptosis in certain human tumor cells.

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PY2252

规格:

5μg, 20μg, 100μg, 500μg, 1mg

价格:

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期:

3-4天

订购信息:

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