BAX Ab

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BAX Ab
Western blot detection of Bax in COS7,Raji,CEM and Hela cell lysates using Bax mouse mAb (1:1000 diluted). Predicted band size:20KDa. Observed band size:20KDa.
BAX Ab
BAX Ab
BAX Ab
BAX Ab
BAX Ab
BAX Ab
BAX Ab
BAX Ab
BAX Ab
BAX Ab
BAX Ab

产品简介

产品简介

Catalog No.

AB3280

Source

Mouse mAb

UniProt ID

Reactivity

Human;Monkey

Application

WB

Calculated Mol Weight

21 kDa

Observed Mol Weight

20 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4

Host

Mouse

Isotype

Mouse IgG2a

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human BAX

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.

引用文献

引用文献

期刊名称:

INTERNATIONAL IMMUNOPHARMACOLOGY

PMID:

35286916

影响因子:

5.714

应用范围:

WB

检测物种:

Human

发表时间:

2024-09-27

期刊名称:

Anti-Cancer Agents in Medicinal Chemistry

PMID:

37005535

影响因子:

2.8

应用范围:

WB

检测物种:

Human

发表时间:

2024-09-27

期刊名称:

Antioxidants

PMID:

38790612

影响因子:

6

应用范围:

WB

检测物种:

Pig

发表时间:

2024-09-27

期刊名称:

MOLECULAR PHARMACEUTICS

PMID:

38857525

影响因子:

4.5

应用范围:

WB,IF

检测物种:

Mouse

发表时间:

2024-08-02

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AB3280

规格:

20μl, 50μl, 100μl

价格:

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期:

3-4天

订购信息:

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