CBX5 Ab

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CBX5 Ab
Western blot detection of HP1 alpha in MCF7,293T,HelaNE,3T3,C6,COS7 and Mouse brain lysates and using HP1 alpha mouse mAb (1:1000 diluted).Predicted band size: 22KDa.Observed band size: 22KDa
CBX5 Ab
Immunohistochemical analysis of paraffin-embedded human breast carcinoma with HP1 alpha mouse mAb (3G2-H10-A6, 1:100 diluted ),showing nuclear localization.A high pressure mediated antigen retrieval step was performed in citrat buffer(pH6.0).
CBX5 Ab
Immunofluorescent analysis stain of Hela using HP1 alpha mouse mAb (1:200).
CBX5 Ab
CBX5 Ab
CBX5 Ab
CBX5 Ab
CBX5 Ab
CBX5 Ab
CBX5 Ab
CBX5 Ab
CBX5 Ab

产品简介

产品简介

Catalog No.

AB3114

Source

Mouse mAb

UniProt ID

Reactivity

Human;Mouse

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

22 kDa

Observed Mol Weight

22 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

ICC/IF 1:50-1:200

IHF 1:50-1:100

Alternative Names

CBX5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha;

Host

Mouse

Isotype

Mouse IgG2b

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human CBX5

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

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AB3114

规格:

20μl, 50μl, 100μl

价格:

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期:

3-4天

订购信息:

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